Heracleum mantegazzianum, commonly known as giant hogweed, is a monocarpic perennial herbaceous plant in the carrot family Apiaceae. H. mantegazzianum is also known as cartwheel-flower, giant cow parsley, giant cow parsnip, or hogsbane. In New Zealand, it is also sometimes called wild parsnip (not to be confused with Pastinaca sativa) or wild rhubarb.

Giant hogweed is native to the western Caucasus region of Eurasia. It was introduced to Britain as an ornamental plant in the 19th century, and has also spread to other areas in Western Europe, the United States, and Canada. Its close relatives, Sosnowsky's hogweed and Persian hogweed, have similarly spread to other parts of Europe.

The sap of giant hogweed is phototoxic and causes phytophotodermatitis in humans, resulting in blisters and scars. These serious reactions are due to the furanocoumarin derivatives in the leaves, roots, stems, flowers, and seeds of the plant. Consequently, it is considered to be a noxious weed in many jurisdictions.